Astragalus membranaceus, also known as Huangqi in China, is one of the most widely used medicinal herbs in Tradi- tional Chinese Medicine. Traditional Chinese Medicine formulations from Astragalus membranaceus have been used to treat a wide range of illnesses, such as cardiovascular disease, type 2 diabetes, nephritis and cancers. Pharmacological studies have shown that immunomodulating, anti-hyperglycemic, anti-inflammatory, antioxidant and antiviral activities exist in the extract of Astragalus membranaceus.
Since there is no available reference genome currently, we adopted Cogent pipeline to assemble a "fake genome" and used SUPPA to analyze Alternative Splicing events from Iso-Seq data (SRP101901). For details, see reference or click the pipeline tab from the navigation bar.
The genome assembled by Cogent included 24,523 sequences, and we found 56,937 transcripts and 14,877 Alternative Splicing events.
- https://www.nature.com/articles/celldisc201731
Type | Skipping Exon (SE) | Alternative 3' Splice Sites (A3) | Alternative 5' Splice Sites (A5) | Retained Intron (RI) | Mutually Exclusive Exons (MX) |
---|---|---|---|---|---|
Gene Number | 372 | 1362 | 1122 | 3785 | 20 |